Figure 6

IDH1 mutation overrides the dependency on EGF and HGF in IBOs. (A) Representative images of IBOs at 5 d after plating (10,000 cells per well), in the presence (Complete) or absence (-EH) of EGF and HGF. Scale bars, 500 μm. (B) The number of organoids (>100 μm) in each group (n = 3, **P < 0.01).