Figure 1

OCA of normal skin, peri-tumoral region and BCC lesion itself prior to PDT. (A) Skin photograph showing the locations of OCA imaging: normal facial cheek skin distant from the tumor and treatment field (green square), visually inflamed peri-tumoral region (blue square) that was included in the 5-mm margin illumination field, and BCC tumor center (yellow square). (B) Corresponding en-face OCA images, showing increasing density and disordered microvascular network in the progression from normal to tumorous tissue.