Figure 8
Overview of the comprehensive analysis strategy for the evaluation of biomaterials in bone regenerative therapy. The natural or synthetic biomaterial is incubated on the CAM of the chicken egg. The neo-vascularization of the scaffold is examined by MRI for its functionality, by MicroCT for the vascular architecture and by histology for the vascular pattern. Together, these quantitative results provide a comprehensive assessment of the ingrown blood vessels. The methods used are presented in tabular form and an in-depth evaluation of the individual layers of the scaffold as well as the advantages and technical limitations of each method are listed.
