Figure 3 | Scientific Reports

Figure 3

From: Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation

Figure 3

Histology of islet xenografts on DPT184. (a) The islet graft was heavily infiltrated by several types of immune cells in R080. Immune cells largely consisted of CD3+ T cells. Both CD4+ and CD8+ cells infiltrated the graft. CD68+ cells were also observed. Black arrowheads indicate intra-graft infiltrating T cells. The scale bar applies universally. (b) Immunofluorescence staining against insulin (red), fibrinogen, and monkey IgG (left and right, respectively; both green). Blue denotes nuclei stained by DAPI. The scale bar applies universally.

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