Table 3 The closeness centrality and the degree of GLPAPs in immune system.

From: Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation

ID

Name

Closeness centrality

Degree

mcc04660

T cell receptor signaling pathway

0.6

21

mcc04662

B cell receptor signaling pathway

0.59302326

20

mcc04611

Platelet activation

0.46788991

11

mcc04664

Fc epsilon RI signaling pathway

0.49514563

8

mcc04650

Natural killer cell mediated cytotoxicity

0.45945946

7

mcc04062

Chemokine signaling pathway

0.43589744

7

mcc04670

Leukocyte transendothelial migration

0.43220339

5

mcc04621

NOD-like receptor signaling pathway

0.33774834

1

  1. The average closeness centrality and the average degree of all GLPAPs in the network were 0.4669 and 8.65 respectively and the values were used as the cutoff values to determine if a GLPAP was meaningful in the pathway interaction network. Only T cell receptor signaling pathway, B cell receptor signaling pathway, and Platelet activation satisfied the cutoff values. The pathways are highlighted by underlines.
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