Figure 5
From: Dynamics, nanomechanics and signal transduction in reelin repeats
PRS analysis of BEB6 module. The PRS map illustrates the strongest perturbation (in dark red), which describes the effect of perturbing residue i on the dynamics of residue j. Sensitivity and effectiveness profiles are shown along the top and right sides. The highest values on a sensitivity profile correspond to the strongest sensors and the highest values of effectiveness correspond to the strongest effectors. Both profiles are displayed on the crystal structure of BEB5. Ca2+ and Zn2+ ions are denoted by orange and red spheres, respectively. Yellow arrows show the binding sites of ApoER2.
