Figure 2
From: Distinct mechanisms of signal processing by lamina I spino-parabrachial neurons
Input-output characteristics of SPNs. (Aa–c), spike discharges evoked in an LO-SPN, an MO-SPN and an HO-SPN by gradually stimulating dorsal roots. The strength of the current pulse is indicated near to the corresponding trace; open and filled arrows indicate 50 µs and 1 ms pulses, respectively. (Ba), the input-output characteristics of the LO-, MO-, and HO-SPNs. Each point represents the mean number of spikes evoked in each type of neuron at a given intensity of the dorsal root stimulation (WDR, wide dynamic range MO-SPNs; NS, nociceptive-specific MO-SPNs). (Bb), the relative contribution of the LO-, MO- and HO-SPNs to the total number of spikes generated by the entire population of SPNs as a function of the stimulation strength in the C-fiber range (1 ms).
