Table 2 Power spectral density changes in the Delta and the Theta band during stimulations with graded hypercapnia and NMDA. Data are expressed as % of baseline (mean ± SD). *p < 0.05, **p < 0.01.
From: NMDA attenuates the neurovascular response to hypercapnia in the neonatal cerebral cortex
Delta (%) | ||||||
|---|---|---|---|---|---|---|
Cortical depth (µm) | 5% CO2 | 10% CO2 | 0.1 mM NMDA | 1 mM NMDA | 5% CO2 | 10% CO2 |
100 | 140.9 ± 14.3* | 58.6 ± 17.4 | 76.2 ± 10.2 | 252.1 ± 54.3** | 51.2 ± 5.1 | 50.5 ± 12.3 |
200 | 130.4 ± 9.2* | 20 ± 3.1 | 44.7 ± 5.1 | 243.6 ± 49.2** | 46.0 ± 8.2 | 22.3 ± 2.0 |
300 | 123.9 ± 23.6* | 18.7 ± 3.1 | 46.8 ± 4.1 | 187.0 ± 14.3** | 45.3 ± 10.3 | 39.5 ± 11.3 |
400 | 127.9 ± 28.7* | 46.5 ± 8.2 | 113.4 ± 11.3 | 305.0 ± 78.9** | 78.5 ± 12.3 | 68.2 ± 23.6 |
500 | 79.8 ± 13.3 | 54.3 ± 8.2 | 92.5 ± 5.1 | 191.1 ± 14.3** | 66.6 ± 11.3 | 59.6 ± 18.4 |
600 | 71.1 ± 7.2 | 44.1 ± 12.3 | 90.3 ± 7.2 | 197.7 ± 15.4** | 60.8 ± 16.4 | 50.3 ± 25.6 |
700 | 38.0 ± 3.1 | 24.1 ± 7.2 | 49.9 ± 5.1 | 160.6 ± 11.3** | 24.4 ± 2.0 | 34.8 ± 8.2 |
800 | 73.4 ± 14.3 | 60.4 ± 29.7 | 113.0 ± 10.2 | 140.9 ± 18.4* | 82.1 ± 8.2 | 77.0 ± 5.1 |
900 | 52.1 ± 5.1 | 46.1 ± 10.2 | 67.3 ± 3.1 | 66.7 ± 10.2 | 97.9 ± 21.5 | 65.6 ± 13.3 |
1000 | 29.7 ± 4.1 | 26.6 ± 6.1 | 37.7 ± 1.0 | 54.2 ± 7.2 | 31.6 ± 8.2 | 31.0 ± 6.1 |
1100 | 83.0 ± 7.2 | 39.3 ± 10.2 | 103.8 ± 5.1 | 74.0 ± 19.5 | 61.7 ± 9.2 | 53.3 ± 10.2 |
1200 | 40.8 ± 6.1 | 31.5 ± 10.2 | 33.7 ± 3.1 | 40.7 ± 7.2 | 27.2 ± 4.1 | 52.1 ± 14.3 |
1300 | 65.7 ± 5.1 | 40.6 ± 8.2 | 56.4 ± 2.0 | 75.7 ± 14.3 | 42.3 ± 4.1 | 50.6 ± 7.2 |
1400 | 55.3 ± 6.1 | 41 ± 7.2 | 45.1 ± 2.0 | 80.8 ± 21.5 | 38.4 ± 3.1 | 65.3 ± 12.3 |
1500 | 52.7 ± 3.1 | 27.7 ± 2.0 | 60.1 ± 3.1 | 58.4 ± 9.2 | 45.8 ± 8.2 | 36.3 ± 8.2 |
1600 | 64.2 ± 5.1 | 35.2 ± 4.1 | 61.6 ± 7.2 | 84.0 ± 14.3 | 40.1 ± 4.1 | 34.5 ± 7.2 |
Theta (%) | ||||||
100 | 184.4 ± 14.3** | 32.1 ± 5.1 | 61.9 ± 3.1 | 59.0 ± 11.3 | 43.2 ± 4.1 | 24.7 ± 3.1 |
200 | 174.2 ± 13.3** | 22.7 ± 2.0 | 80.5 ± 6.1 | 38.1 ± 9.2 | 42.4 ± 3.1 | 21.6 ± 3.1 |
300 | 163.7 ± 14.3** | 19.1 ± 1.0 | 59.0 ± 4.1 | 51.3 ± 8.2 | 37.9 ± 3.1 | 31.5 ± 4.1 |
400 | 160.1 ± 18.4** | 24.5 ± 3.1 | 76.8 ± 6.1 | 57.7 ± 11.3 | 42.2 ± 4.1 | 30.6 ± 4.1 |
500 | 157.5 ± 14.3** | 30.3 ± 5.1 | 51.2 ± 3.1 | 42.5 ± 8.2 | 31.3 ± 3.1 | 29.1 ± 6.1 |
600 | 165.4 ± 18.4** | 21.7 ± 2.0 | 108.9 ± 9.2 | 61.7 ± 11.3 | 42.4 ± 4.1 | 31.8 ± 3.1 |
700 | 105.0 ± 15.4 | 58.5 ± 12.3 | 77.7 ± 6.1 | 67.1 ± 11.3 | 41.1 ± 3.1 | 38.4 ± 4.1 |
800 | 105.1 ± 12.3 | 19.9 ± 1.0 | 81.2 ± 6.1 | 56.8 ± 10.2 | 49.1 ± 7.2 | 40.9 ± 7.2 |
900 | 114.1 ± 11.3 | 29.9 ± 3.1 | 96.9 ± 7.2 | 57.4 ± 9.2 | 65.4 ± 4.1 | 41.9 ± 5.1 |
1000 | 167.5 ± 11.3** | 22.3 ± 2.0 | 91.9 ± 6.1 | 63.9 ± 10.2 | 53.1 ± 4.1 | 44.5 ± 8.2 |
1100 | 157.7 ± 12.3** | 19.4 ± 2.0 | 86.7 ± 7.2 | 59.1 ± 9.2 | 55.6 ± 3.1 | 50.4 ± 8.2 |
1200 | 154.0 ± 12.3** | 24.5 ± 2.0 | 100.8 ± 7.2 | 55.3 ± 9.2 | 56.9 ± 3.1 | 44.0 ± 7.2 |
1300 | 114.5 ± 15.4 | 22.3 ± 2.0 | 98.1 ± 6.1 | 54.0 ± 7.2 | 64.3 ± 4.1 | 61.9 ± 1.0 |
1400 | 109.5 ± 17.4 | 17.7 ± 1.0 | 83.9 ± 5.1 | 52.0 ± 7.2 | 59.3 ± 3.1 | 40.9 ± 6.1 |
1500 | 101.5 ± 16.4 | 19 ± 2.0 | 82.0 ± 6.1 | 45.8 ± 7.2 | 60.4 ± 4.1 | 32.4 ± 4.1 |
1600 | 104.1 ± 16.4 | 32.7 ± 3.1 | 71.3 ± 5.1 | 62.5 ± 7.2 | 56.2 ± 3.1 | 48.9 ± 6.1 |
