Table 2 Correlations between DAMP concentration and clinical characteristics in all study subjects.

From: Differential DAMP release was observed in the sputum of COPD, asthma and asthma-COPD overlap (ACO) patients

Characteristic

HSP70

Gal-3

S100A8

LL-37

HMGB1

BMI

0.001

−0.009

−0.080

−0.064

−0.179*

Smoking pack-years

0.188

−0.277**

0.181*

0.295**

0.343**

Age

0.004

−0.073

0.097

0.208**

0.124

FEV1 (L)

−0.169*

0.279**

−0.687**

−0.328**

−0.637**

FEV1 pred (%)

−0.173

0.278**

−0.685**

−0.376**

−0.698**

FEV1/FVC (%)

−0.173

0.312**

−0.468**

−0.366**

−0.669**

∆FEV1 (%)

0.123

−0.066

−0.057

−0.176*

0.096

TCC (106/ml)

0.101

−0.276**

0.730**

0.377**

0.668**

Macrophages (%)

−0.180*

0.237**

−0.366**

−0.291**

−0.566**

Neutrophils (%)

0.194**

−0.227**

0.385**

−0.357**

0.543**

Lymphocytes (%)

0.003

−0.041

−0.030

−0.164*

0.096

  1. Study participants (N = 352). Data are Spearman rank correlation coefficients between variables. BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity;*p < 0.05; **p < 0.01.
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