Figure 1

Structure of holo-GABA GabR dimer. Cartoon colors indicate the different domains in the two subunits: orange indicate the wHTH domains; pale cyan the two linkers; dark and light green the AAT domains. PLP-GABA adducts are displayed as stick models enclosed in transparent space filling representation. Ovals enclose the small subdomain of each AAT domain. Curley brackets highlight the linker position. Structure of the 5T4J AAT domains, superposed to the corresponding holo-GABA GabR chains, is displayed as light pink transparent cartoon. This figure has been created with the software open-source PyMOL v. 1.8.4.0 (https://pymol.org/)55.