Table 2 Effect of Copaxone on disease severity in HLA-DR3.DQ8 Tg mice immunized with PLP91–110.

From: Scoring disease in an animal model of multiple sclerosis using a novel infrared-based automated activity-monitoring system

Treatment

Disease Incidence (%)

Mean onset of disease ± SD

Mean EAE Score ± SD

Number of mice with maximum severity score

0

1

2

3

4

5

PBS-IFA

7/7 (100%)

9.8 ± 0.98

30.14 ± 4.87

—

—

—

—

6

1

Copaxone

9/8 (89%)

12.37 ± 1.59

10.29 ± 5.95

1

2

4

2

—

—

  1. Statistical analyses were done with GraphPad Prism 7.
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