Table 3 Relationship between the FTO polymorphism and obesity status in MS patients using both an additive and a recessive genetic model.
SNP | Model | Normal weight | Overweight/obese | ORa (95% CIb) | p-value |
|---|---|---|---|---|---|
FTO rs9939609 | Additive | ||||
TT | 28 (33.7%) | 31 (26.5%) | |||
TA | 43 (51.8%) | 51 (43.6%) | 1.51 (1–2.28) | 0.04 | |
AA | 12 (14.5%) | 35 (29.9%) | |||
Recessive | |||||
TT/TA | 71 (85.5%) | 82 (70.1%) | |||
AA | 12 (14.5%) | 35 (29.9%) | 2.48 (1.17–5.29) | 0.01 | |