Figure 2
From: Imaging of X-Ray-Excited Emissions from Quantum Dots and Biological Tissue in Whole Mouse
X-ray-excited NIR emission from whole mouse cadaver, recorded on EM-CCD. (a) (Greyscale) Ambient-light NIR image of mouse cadaver which has been injected at two points with CdTe QD suspensions having λemission = 715 nm, and (colour) superimposed detected 715 nm NIR emission excited by X-rays at 55 kVp. (A small number of pin-point artefacts exist due to scattered X-rays). The X-ray source is overhead, at 50 cm SSD. The yellow lines mark the boundary of an ROI examined in (b). (b) Cross-section showing the number of X-ray-excited NIR photons detected over the 26 rows in the ROI of the image in (a). (c) UV-excited QD emission (colour) superimposed on ambient-light image (greyscale). The UV source is directly overhead, as for the X-ray source that excited image (a), but due to UV absorption by the whole-mouse tissue and bone, no UV excitation of the lower injection zone is achieved, whereas the 55 kVp X-rays readily penetrate this material and produce the QD excitation seen in (a). The images confirm that the X-ray-indicated distribution of QDs matches that inferred by conventional UV excitation for the upper injection zone. (d) Schematic to aid the interpretation of images (a,c), showing the regions of the two shallow QD injections, plus the eye, ear (folded forward), and forearm (the paw is tucked under and not visible).
