Table 4 Factors associating with lamina cribrosa defect in highly myopic eyes (26 mm ≤ axial length <27 mm).

From: Bruch’s membrane opening enlargement and its implication on the myopic optic nerve head

Variables

Univariate

Multivariate (Model 1)

Multivariate (Model 2)

Multivariate (Model 3)

Odds Ratio

(95% CI)

P-value

Odds Ratio

(95% CI)

P-value

Odds Ratio

(95% CI)

P-value

Odds Ratio

(95% CI)

P-value

IOP

1.406 (1.075, 1.839)

0.013

1.315 (1.006, 1.719)

0.045

1.301 (1.004, 1.699)

0.046

1.506 (1.123, 2.020)

0.006

Anterior laminar depth

1.008 (1.001, 1.015)

0.019

1.005 (0.997, 1.014)

0.184

1.004 (0.997, 1.012)

0.264

1.004 (0.996, 1.011)

0.314

BMO area

3.752 (1.548, 9.090)

0.003

2.728 (1.119, 6.653)

0.017

    

PPA−BM width

1.004 (1.001, 1.007)

0.006

  

1.003 (0.999, 1.006)

0.163

  

Global BMO-MRW

0.978 (0.961, 0.995)

0.012

    

0.973 (0.953, 0.993)

0.010

  1. CI = confidence interval; IOP = intraocular pressure; BMO = Bruch’s membrane opening; PPA−BM = β-parapapillary atrophy without Bruch’s membrane; MRW = minimum rim width.
  2. Factors with statistical significance are shown in boldface.
  3. P values were adjusted with Benjamini-Hochberg procedure.
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