Figure 3
From: Untargeted LC-HRMS-based metabolomics to identify novel biomarkers of metastatic colorectal cancer
Representative chromatogram of m/z 302.3042 in a biological sample (A) and sphinganine standard (B) at 10.13 min. Characteristic MS/MS spectra of m/z 302.3042 in a biological sample (C) and sphinganine standard at 10.13 min, and fragment interpretation (D). MS/MS spectra reveal the characteristic fragmentation pattern of sphinganine. Fragment ions at m/z 284 and 266 have previously been described as a single dehydration and a double dehydration, respectively. It should be noted that the single dehydration product is much more abundant than the double dehydration product, which is also a characteristic pattern.
