Figure 2 | Scientific Reports

Figure 2

From: Discordant gene responses to radiation in humans and mice and the role of hematopoietically humanized mice in the search for radiation biomarkers

Figure 2

Heat map of predicted transcriptional regulators upstream of opposite microarray gene expression changes. All regulatory proteins shown here were predicted to be involved in the regulation of the set of genes showing opposite activities in humans and mice at ~4 Gy dose of radiation. The deeper the color (blue for inactivation and orange for activation as determined by the z-score) the stronger the predicted activation/inactivation status of the regulatory protein, as shown in the key (z-scores are shown in Supplemental Table S1, tab 2).

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