Figure 1

Organization of silica and collagen in multiphasic xerogels (by the example B30). SEM images of agglomerated spherical silica particles (a), collagen fibrils arranged in parallel in the silica/collagen matrix, as well as fibril bundle (b), and filamentary bondings of low fibrillar collagen organized in between silica agglomerates (c, higher magnification of selection in inset). Bright field TEM image of silica/collagen matrix (d) and related EDX spectrum (d, inset). Dark field TEM image of two collagen fibrils in parallel within silica/collagen matrix (e) and related EDX spectrum (e, inset). Intensity profile of the line scan (f) along the black arrow in (e) indicating two silica sheathed collagen fibrils. Agglomerated silica particles were exemplarily indicated with stars, low fibrilar collagen with arrows and collagen fibrils with asterisks.