Table 3 List of down-regulated proteins after the treatment of OGS irradiation compared to the control.

From: Proteomic profiling and identification of significant markers from high-grade osteosarcoma after cryotherapy and irradiation

S.NO

Description

Accession

Avg. Mass

Significance

Coverage (%)

#Peptides

#Unique

OGS

Control Area

OGSLN Area

OGSRAD Area

P-Value

Down-regulated proteins after Irradiation treatment

1

Endoplasmic reticulum chaperone BiP

P11021

72333

132

10

5

2

1.48E + 07

5.97E + 06

1.69E + 07

0.001

2

Cathepsin B

P07858

37822

132.88

5

1

1

5.58E + 06

5.05E + 06

1.59E + 07

0.001

3

Glutathione S-transferase P

P09211

23356

200

8

1

1

2.05E + 07

3.86E + 06

2.77E + 07

0.001

4

Collagen alpha-2(I) chain

P08123

129314

130.34

2

1

1

1.73E + 06

6.16E + 05

3.11E + 06

0.001

5

Filamin-A

P21333

280737

121.83

3

6

4

1.07E + 07

5.24E + 06

1.29E + 07

0.001

6

Alpha-enolase

P06733

47169

79.24

29

9

2

1.67E + 07

1.20E + 07

2.87E + 07

0.001

7

Transaldolase

P37837

37540

11.26

9

4

2

5.26E + 06

4.11E + 06

9.62E + 06

0.001

8

Immunoglobulin gamma-1 heavy chain

P0DOX5

49329

11.21

27

11

2

5.13E + 07

2.01E + 07

5.31E + 07

0.001

9

Protein disulfide-isomerase A3

P30101

56782

36.97

5

2

1

1.77E + 07

1.06E + 07

9.84E + 07

0.001

10

Alpha-1-acid glycoprotein 2

P19652

23603

12.51

5

1

1

8.34E + 05

6.97E + 05

2.58E + 06

0.001

  1. LN: Liquid Nitrogen; OGS: Osteosarcoma RAD: Irradiation/ECIR, FDR: False Discovery Rate.