Figure 4

Significantly improved classification rate of Staphylococcus (sub)species for SLST compared to 16S. (A) Skin 16S V3-V4 sequencing data shows a significant increase for AD patients in Staphylococcus genus-level assigned reads in the dataset in comparison to HC (p = 0.002) (also see Suppl. Fig. S9), which is in line with literature27. (B) When evaluating the percentage of (sub)species-level assigned reads, that is, number of total Staphylococcus reads that could be classified to species level or lower, we observe a significant increased classification rate for SLST in comparison to 16S (p < 0.0001). Boxplots as median with interquartile range and whiskers from min to max. Blue dots represent individual data points.