Figure 2
From: 3D bioprinting via an in situ crosslinking technique towards engineering cartilage tissue
NorHA bioink composition and crosslinking. (a) Chemical structures of components incorporated into NorHA bioinks and their (b) absorption spectra, including for NorHA (2 wt%, square), LAP (0.05 wt%, circle), DTT (0.08 wt%, diamond), and their combination into a single bioink formulation (triangle). (c) Schematic of thiol-ene reaction employed to crosslink the NorHA bioink in the presence of visible light and LAP photoinitiator. (d) Representative photorheology time sweep (1 Hz, 0.5% strain) during the photocrosslinking of the NorHA bioink with visible light (400–500 nm) at I1 = 10 mW/cm2, illustrating increases in storage (G′, closed circles) and loss (G″, open circles) moduli over time.
