Table 1 Characteristics of 261 patients with 331 CCMs treated with GKS between 1993 and 2018.
From: Gamma Knife radiosurgery for cerebral cavernous malformation
Characteristic | No. (percentage or range) |
|---|---|
Age in yrs (range) | 39.9 (7.4–75.3) |
Gender (% female) | 141 (54) |
Total no. of CCMs | 331 |
No. of CCMs by location | |
Brainstem | 111 (33.5) |
Basal ganglion/thalamus | 47 (14.2) |
Cortical/subcortical | 115 (34.7) |
Cerebellum/4th ventricle | 41 (12.4) |
Multiple lesions | 17 (5.1) |
No. of pre-GKS hemorrhages (% of 261 total) | |
1 | 149 (57.1) |
2 | 99 (37.9) |
3 | 9 (3.5) |
4 | 2 (0.8) |
5 | 1 (0.4) |
>5 | 1 (0.4) |
CCM volume (cm3) | 3.1 (0.03–28.9) |
Symptoms | |
Hemisensory deficit | 194 (74.3) |
Cranial nerve deficits | 187 (71.7) |
Hemiparesis | 124 (47.5) |
Headache | 79 (30.3) |
Dizziness | 60 (23.0) |
Seizure | 36 (13.8) |
Clinical follow-up median (months) | 68.9 (6–280) |
Image follow-up median (months) | 60.7 (6–266) |
GKS Parameters (mean) | |
Margin dose (Gy) | 11.9 (8.5–18.0) |
Max dose (Gy) | 20.3 (10.9–35.0) |
Isodose level (%) | 59 (50–90) |
