Table 3 Variables associated with the interval of intravitreal dexamethasone implant and recurrence of diabetic macular edema in linear regression analyses.

From: Factors associated with the duration of action of dexamethasone intravitreal implants in diabetic macular edema patients

  

Univariate analyses*

multivariate analyses*†

β ± SE

p-value

β ± SE

p-value

Aqueous humor

IL-1 β level (pg/mL)

−0.091 ± 0.101

0.371

  

IL-8 level (pg/mL)

−0.021 ± 0.007

0.010

−0.016 ± 0.006

0.037

IL-10 level (pg/mL)

−0.170 ± 0.200

0.401

  

IL-17 level (pg/mL)

0.080 ± 0.097

0.412

  

VEGF level (pg/mL)

−0.001 ± 0.003

0.802

  

PlGF level (pg/mL)

−0.055 ± 0.060

0.369

  

OCT findings

Number of HF

−0.111 ± 0.033

0.002

−0.073 ± 0.034

0.035

EZ disruption grade

−0.113 ± 0.215

0.604

  

CST before injection (μm)

−0.004 ± 0.002

0.017

−0.003 ± 0.002

0.061

Presence of SRD

0.058 ± 0.411

0.888

  
  1. *Adjusted for age, sex.
  2. IL, interleukin; VEGF, vascular endothelial growth factor; PlGF, placental growth factor; HF, hyperreflective foci; EZ, ellipsoid zone; CST, central subfield thickness; SRD, Serous retinal detachment.
  3. †R2 = 0.326.
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