Figure 8 | Scientific Reports

Figure 8

From: Probabilistic Assessment of Nerve Regeneration with Diffusion MRI in Rat Models of Peripheral Nerve Trauma

Figure 8

Representative distal toluidine blue stained sections at 2 (top panel), 4 (middle panel) and 12 weeks (bottom panel) after each injury type. In the sham groups (left column), there was little difference between the three times, except for some evidence of extra-cellular edema at 2 weeks. In contrast, crush nerves (middle column) shows indications of degeneration at 2 weeks and full recovery by 4 weeks. For the cut/repair group (right column), severe degeneration is observed at 2 and 4 weeks. By 12 weeks, a subset of cut/repair nerves showed little recovery (“non-recovered” panel), while another subset showed partial recovery (“recovered” panel). The scale bar in the bottom-right panel represents 50 μm.

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