Table 2 Reactivity and specificity of the pneumococcal serotyping LAMP assay.
Vaccine | Serotypes | No. of strains | Strain ID | Origin of isolate | LAMP primer set | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
4 | 6B | 9V | 14 | 18C | 19F | 23F | 1 | 3 | 5 | 7F | 19A | |||||
PCV7 | 4 | 2 | SP0852, SP0143 | RTa, CSF | +b | — | — | — | — | — | — | — | — | — | — | — |
6B | 2 | SP0857, SP1489 | N, N | — | + | — | — | — | — | — | — | — | — | — | — | |
9V | 2 | SP0916, SP2928 | N, B | — | — | + | — | — | — | — | — | — | — | — | — | |
14 | 2 | SP0869, SP3320 | N, B | — | — | — | + | — | — | — | — | — | — | — | — | |
18C | 2 | SP0873, SP2818 | N, B | — | — | — | — | + | — | — | — | — | — | — | — | |
19F | 2 | SP0862, SP1118 | N, N | — | — | — | — | — | + | — | — | — | — | — | — | |
23F | 2 | SP0885, SP2838 | N, N | — | — | — | — | — | — | + | — | — | — | — | — | |
PCV13 | 1 | 2 | SP3121, SP3070 | B, B | — | — | — | — | — | — | — | + | — | — | — | — |
3 | 2 | SP1441, SP3256 | N, N | — | — | — | — | — | — | — | — | + | — | — | — | |
5 | 2 | SP3034, ATCC6305 | U, U | — | — | — | — | — | — | — | — | — | + | — | — | |
6A | 2 | SP1567, SP1589 | N, N | — | + | — | — | — | — | — | — | — | — | — | — | |
7F | 2 | SP3365, SP3172 | B, RT | — | — | — | — | — | — | — | — | — | — | + | — | |
19A | 2 | SP1516, SP3081 | N, N | — | — | — | — | — | — | — | — | — | — | — | + | |
PPSV23 | 2 | 1 | D39 | U | — | — | — | — | — | — | — | — | — | — | — | — |
8 | 1 | ATCC6308 | U | — | — | — | — | — | — | — | — | — | — | — | — | |
9N | 1 | SP2700 | CSF | — | — | — | — | — | — | — | — | — | — | — | — | |
10A | 1 | SP1933 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
11A/E | 1 | SP2760 | RT | — | — | — | — | — | — | — | — | — | — | — | — | |
12F | 1 | SP0113 | B | — | — | — | — | — | — | — | — | — | — | — | — | |
15B | 1 | SP3354 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
17F | 1 | NCTC11904 | U | — | — | — | — | — | — | — | — | — | — | — | — | |
20 | 1 | SP2830 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
22F | 1 | SP1854 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
33F | 1 | SP3201 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
Non- vaccine serotypes | 6C | 1 | SP3362 | N | — | + | — | — | — | — | — | — | — | — | — | — |
6D | 1 | SP2739 | N | — | + | — | — | — | — | — | — | — | — | — | — | |
7A | 1 | 2040/37 | U | — | — | — | — | — | — | — | — | — | — | + | — | |
7C | 1 | SP3285 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
9A | 1 | Wilder | U | — | — | + | — | — | — | — | — | — | — | — | — | |
13 | 1 | SP0073 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
15A | 1 | SP2758 | RT | — | — | — | — | — | — | — | — | — | — | — | — | |
15C | 1 | SP3343 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
18A | 2 | SP0852, 8609/43 | B, U | — | — | — | — | + | — | — | — | — | — | — | — | |
18B | 1 | SP1901 | N | — | — | — | — | + | — | — | — | — | — | — | — | |
18F | 1 | Lederle | U | — | — | — | — | + | — | — | — | — | — | — | — | |
23A | 1 | SP3374 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
24F | 1 | SP3193 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
34 | 1 | SP3359 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
35B | 1 | SP3357 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
37 | 1 | SP2742 | N | — | — | — | — | — | — | — | — | — | — | — | — | |
38 | 1 | SP3356 | N | — | — | — | — | — | — | — | — | — | — | — | — | |