Table 1 Summary of the immunohistochemical analysis of nuclear YAP1 and TAZ expression in tumors of soft tissue and bone.

From: Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone

Type

n

YAP1

TAZ

Angiosarcoma (AS)

29

7 (24%)

16 (55%)

Ewing sarcoma (EwS)

20

4 (20%)

3 (15%)

Leiomyosarcoma (LMS)

68

30 (44%)

5 (7%)

Malignant peripheral nerve sheath tumor (MPNST)

45

26 (58%)

32 (71%)

Solitary fibrous tumor (SFT)

36

15 (42%)

3 (8%)

Synovial sarcoma (SySa)

65

51 (78%)

22 (34%)

Well-differentiated liposarcoma (WDLS)

55

21 (38%)

3 (5%)

Dedifferentiated liposarcoma (DDLS)

74

24 (32%)

23 (31%)

Myxoid liposarcoma (MLS)

85

77 (91%)

47 (55%)

Pleomorphic liposarcoma (PLS)

9

3 (33%)

4 (44%)

Total

486

258 (53%)

158 (33%)

  1. Only tumors with at least moderate staining (semiquantitative score ≥2) and ≥30% positive cells were considered positive for the purposes of this study.