Table 2 Associations between ACE I/D polymorphisms and clinical characteristics in STEMI patients.
ACE genotypes | II (n = 65) | ID (n = 89) | DD (n = 45) | |||||
|---|---|---|---|---|---|---|---|---|
Parameters | n | n | Univariate | p* | n | Univariate | p* | |
OR (95% CI) | OR (95% CI) | |||||||
Age (year) <60 | 33 | 1 (ref.) | 45 | 17 | ||||
≥60 | 32 | 44 | 0.983 (0.949–1.013) | 0.232 | 28 | 1.272 (0.574–2.819) | 0.553 | |
BMI (kg/m2) <27 | 29 | 1 (ref.) | 32 | 21 | ||||
≥27 | 36 | 57 | 1.435 (0.747–2.757) | 0.279 | 24 | 0.921 (0.429–1.974) | 0.832 | |
Gender-Female | 40 | 1 (ref.) | 69 | 33 | ||||
Male | 25 | 20 | 0.464 (0.229–0.939) | 0.033 | 12 | 0.582 (0.254–1.332) | 0.200 | |
SBP (mmHg) <140 | 57 | 1 (ref.) | 77 | 41 | ||||
≥140 | 8 | 12 | 1.110 (0.426–2.894) | 0.830 | 4 | 0.695 (0.196–2.464) | 0.573 | |
DBP (mmHg) <90 | 33 | 1 (ref.) | 50 | 29 | ||||
≥90 | 32 | 39 | 8.874 (0.263–15.787) | 0.129 | 16 | 6.244 (0.674–57.842) | 0.107 | |
Hypertension-No | 33 | 1 (ref.) | 40 | 25 | ||||
Yes | 32 | 49 | 1.263 (0.665–2.398) | 0.475 | 20 | 0.569 (0.261–1.242) | 0.157 | |
Diabetes-No | 52 | 1 (ref.) | 69 | 41 | ||||
Yes | 13 | 20 | 1.159 (0.529–2.543) | 0.712 | 4 | 0.390 (0.118–1.287) | 0.122 | |
Smoking-No | 40 | 1 (ref.) | 69 | |||||
Yes | 25 | 20 | 2.715 (1.404–5.250) | 0.003 | 2.635 (1.205–5.765) | 0.015 | ||
WBC (109/l) | 10.1 ± 3.3 | 1 (ref.) | 10.3 ± 2.8 | 0.944 (0.850–1.049) | 0.284 | 10.1 ± 3.1 | 0.899 (0.790–1.022) | 0.103 |
HDL-c (mmol/l) | 1.1 ± 0.3 | 1 (ref.) | 1.1 ± 0.2 | 0.379 (0.095–1.516) | 0.170 | 1.2 ± 0.2 | 1.558 (0.343–7.073) | 0.566 |
FIB (mmol/l) | 3.1 ± 0.54 | 1 (ref.) | 3.2 ± 0.7 | 1.159 (0.736–1.825) | 0.524 | 3.4 ± 1.0 | 1.477 (0.874–2.496) | 0.145 |
