Figure 6
From: Differentiating external zeitgeber impact on peripheral circadian clock resetting
Changes in food intake and body weight under ZD conditions. (a) Food intake (closed squares) and body weight gain (open squares) throughout 5 weeks of the ZD paradigm. In-phase (solid black lines) and anti-phase days (dashed grey lines) are indicated. (b) Normalized food intake (closed squares) and weight change (open squares) profiles across the ZD cycle. (c) Normalized food consumption, (d) weight gain, and (e) energy conversion on in-phase and anti-phase days. All data are shown as means ± SEM (n = 45, ****p < 0.0001, two-tailed, paired t-tests). (f) Glucose tolerance test over time (left) and calculated area under the curve (right) on in-phase (n = 4) and anti-phase (n = 6) days. Due to technical problems two animals in the in-phase condition had to be excluded. Data are shown as means ± SEM, ***p < 0.001, condition effect §§p < 0.005, time effect $$$$ p < 0.0001, two-way ANOVA.
