Table 2 Combination of colistin, salicylate and BC1 reverses colistin MIC in colistin resistant bacteria (MF-Modulation factor).

From: Restoring colistin sensitivity in colistin-resistant E. coli: Combinatorial use of MarR inhibitor with efflux pump inhibitor

Strains

MIC of colistin (µg/ml)

Colistin + Sal

Colistin + BC1

Colistin + CCCP

Colistin + Sal + BC1

Colistin + Sal + CCCP

MIC (µg/ml)

MF

MIC (µg/ml)

MF

MIC (µg/ml)

MF

MIC (µg/ml)

MF

MIC (µg/ml)

MF

U3790

32

4

8

2

16

4

8

0.25

128

0.25

128

U1007

4

2

2

0.5

8

0.25

16

0.5

8

0.25

16

U2354

2

1

2

0.5

4

0.25

8

0.25

8

0.25

8

U1024

2

1

2

0.5

4

0.125

16

0.25

8

0.25

8

IDH09519

2

1

2

0.5

4

0.125

16

0.25

8

0.25

8

IDH07933

2

1

2

0.5

4

0.125

16

0.25

8

0.25

8

MG1655

2

2

1

0.062

32

2

1

0.062

32

2

1

U3176

1

1

1

0.25

4

0.5

2

0.25

4

0.5

2

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