Figure 6 | Scientific Reports

Figure 6

From: MicroRNA-548 regulates high mobility group box 1 expression in patients with preterm birth and chorioamnionitis

Figure 6

MicroRNA-548 cluster can attenuate lipopolysaccharide (LPS)-induced inflammation in hAECs. (A) HMGB1 mRNA and protein expression in miRNA-548 mimic and control mimic transfected hAECs that were not treated or treated with LPS. (B) HMGB1 levels in culture medium of miRNA-548 mimic and control mimic transfected hAECs that were not treated or treated with LPS. (C) IL-1β, IL-6, and IL-8 levels in culture medium of miRNA-548 mimic and control mimic transfected hAECs that were not treated or treated with LPS. **Significant difference (P < 0.001) compared with control mimic group, *Significant difference (P < 0.001) compared with control group. hAECs, human amniotic epithelial cells; LPS, Lipopolysaccharide; IL, interleukin.

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