Table 1 Most relevant affected pathway by cold exposure.
Classification | Sub-classification | Number of genes | |
|---|---|---|---|
Up-regulated | Down-regulated | ||
Gene expression | |||
Transcription factor | 13 | 53 | |
RNA maturation | 2 | 10 | |
DNA structure | 2 | 9 | |
Epigenetic regulation | 0 | 6 | |
Coactivator | 0 | 5 | |
Post-transcriptional regulation | 0 | 5 | |
Corepressor | 0 | 4 | |
Interfering RNA (siRNA, miRNA) | 0 | 2 | |
RNA degradation | 1 | 0 | |
Others | 2 | 7 | |
Cell cycle | |||
Cell proliferation | 8 | 21 | |
Cell cycle regulation | 9 | 16 | |
Apoptosis | 3 | 6 | |
Cell differentiation | 3 | 6 | |
Cell determination | 1 | 2 | |
Immune response | |||
Immune system maturation/activation | 26 | 17 | |
Antigen recognition/presentation | 5 | 5 | |
Antigen degradation | 3 | 2 | |
Cytokine signalling | 2 | 1 | |
Others | 3 | 3 | |