Table 2 Classification of top 50 regulated genes affected by cold exposure.

From: Effects of cold exposure revealed by global transcriptomic analysis in ferret peripheral blood mononuclear cells

Gene Name

Gene Symbol

Sequence ID

Fold Change

p-value

Gene expression

Zinc Finger BED-Type Containing 5

Zbed5

XM_004751989.2

−2.18

5.58E-04

Trinucleotide Repeat Containing 6A

Tnrc6a

XM_013048889.1

−1.76

2.15E-04

Lysine acetyltransferase 6B

Kat6b

XM_004769363.2

−1.70

3.14E-04

Zinc finger CCHC-type containing 11

Zcchc11

XM_013046839.1

−1.62

7.24E-04

Exportin For TRNA

Xpot

XM_004752498.2

−1.47

8.22E-05

Zinc Finger Protein 770

Znf770

XM_004751051.2

−1.46

3.59E-04

MGA, MAX Dimerization Protein

Mga

XM_004751157.2

−1.44

2.37E-05

Zinc Finger MYM-Type Containing 5

Zmym5

XM_013048828.1

−1.39

1.87E-04

Zinc Finger And SCAN Domain Containing 30

Zscan30

XM_004752298.2

−1.37

3.35E-04

Enhancer Of Polycomb Homolog 1

Epc1

XM_004777872.2

−1.36

4.94E-04

Zinc Finger Protein 235

Znf235

XM_013063895.1

−1.22

7.59E-04

Tubby Like Protein 4

Tulp4

XM_013044950.1

1.56

2.27E-04

Cell cycle

Family with sequence similarity 65 member B

Fam65b

XM_004761237.2

−1.72

7.54E-04

Protein tyrosine phosphatase type IVA, member 3

Ptp4a3

XM_004743631.2

−1.54

2.45E-04

MDM4, p53 regulator

Mdm4

XM_004756399.2

−1.42

6.66E-04

Ubiquitin Specific Peptidase 37

Usp37

XM_004762758.2

−1.33

3.70E-04

Fibronectin type III domain containing 3B

Fndc3b

XM_004756587.2

1.38

6.09E-04

Structural Maintenance Of Chromosomes 1B

Smc1b

XM_004771114.2

1.95

4.15E-04

Death associated protein kinase 1

Dapk1

XM_004774132.2

2.10

1.02E-04

Extracellular matrix/Cytoskeleton

Septin 1

Sept1

XM_004741975.2

−1.95

3.66E-04

BBSome Interacting Protein 1

Bbip1

XM_004763864.1

−1.95

2.24E-04

Coiled-Coil Serine Rich Protein 2

Ccser2

XM_004765771.2

−1.50

3.08E-04

Zinc Finger RANBP2-Type Containing 1

Zranb1

XM_004751744.2

−1.33

3.13E-04

Syntaxin Binding Protein 6

Stxbp6

XM_004755163.2

−1.23

3.72E-04

Immune response

C-type lectin domain family 2 member D

Clec2d

XM_004779708.2

−2.27

8.13E-04

Tripartite Motif Containing 13

Trim13

XM_004775233.2

−1.43

1.19E-04

Sialic Acid Binding Ig Like Lectin 8

Loc101680639

XM_004767130.2

2.44

6.39E-04

Human immunodeficiency virus type I enhancer binding protein 2

Hivep2

XM_013056235.1

−1.89

2.89E-04

Cell transport

TBC1 Domain Family Member 16

Tbc1d16

XM_004748756.2

−1.45

3.09E-04

Stromal Interaction Molecule 2

Stim2

XM_004762647.2

−1.35

6.52E-04

Energy metabolism

UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5

B3gnt5

XM_004745085.2

−1.90

5.68E-04

Nucleotide Binding Protein Like

Nubpl

XM_013047446.1

−1.17

2.81E-04

Signal transduction

Mitogen-Activated Protein Kinase Kinase 6

Map2k6

XM_004749075.2

−1.56

1.70E-04

Dmx Like 2

Dmxl2

XM_004755431.2

2.17

5.59E-04

Enzymes/metabolism

Cysteine Sulfinic Acid Decarboxylase

Csad

XM_004774642.1

−1.46

2.66E-04

Other

Prostate transmembrane protein, androgen induced 1

Pmepa1

XM_004759915.2

−2.26

8.15E-04

Ubiquitin Specific Peptidase 13 (Isopeptidase T-3)

Usp13

XM_004756639.1

−1.68

7.44E-05

Low Density Lipoprotein Receptor Class A Domain Containing 4

Ldlrad4

XM_013051371.1

−1.63

3.90E-04

SUMO1/Sentrin Specific Peptidase 5

Senp5

XM_004745326.2

−1.35

8.18E-04

Tau tubulin kinase 2

Ttbk2

XM_004751214.1

−1.29

4.40E-04

Atlastin GTPase 2

Atl2

XM_004765501.2

−1.27

5.06E-04

Family with sequence similarity 214, member B

Fam214b

XM_013053738.1

1.56

1.44E-04

Lysophosphatidylcholine Acyltransferase 2

Lpcat2

XM_004744201.2

1.90

5.13E-04

Unknown function

Family With Sequence Similarity 214 Member A

Fam214a

XM_004755399.2

−1.94

2.32E-04

Leucine Rich Pentatricopeptide Repeat Containing

Lrpprc

XM_013056345.1

−1.53

5.24E-04

Coiled-Coil Domain Containing 181

Ccdc181

XM_004756660.2

−1.44

4.31E-04

Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)

Pomgnt2

XM_004754292.2

−1.35

7.68E-04

Transmembrane Protein 19

Tmem19

XM_004752428.2

−1.32

1.10E-04

PiggyBac Transposable Element Derived 1

Pgbd1

XM_004779982.2

−1.31

7.76E-04

Family With Sequence Similarity 217 Member B

Fam217b

XM_004759963.2

1.26

1.92E-05

  1. Detailed classification of top 50 regulated genes affected by cold exposure in PBMC vs their respective controls, based on their p-value (Students’ t-test). Fold change: + indicates up-regulation, while − indicates down-regulation by cold exposure. Genes are ordered by fold change. This Table is also available as Supplementary data set in .xlsx format.