Table 1 Clinicopathological characteristics of ESCC patients and identification of prognostic clinical factors.
Clinical characteristics | GSE43732 (N = 119) | Uni-variate cox regression | Multi-univariate cox regression | ||||
|---|---|---|---|---|---|---|---|
HR | 95%CI | P-value | HR | 95%CI | P-value | ||
Age (mean ± SD) | 59.03 ± 8.93 | 1.027 | 0.999–1.057 | 0.06 | — | — | — |
Gender (male/female) | 98/21 | 0.827 | 0.468–1.461 | 0.51 | — | — | — |
Pathologic grade (poorly/moderately/well) | 32/64/23 | 0.819 | 0.575–1.169 | 0.27 | — | — | — |
Pathologic stage (I/II/III) | 6/47/66 | 1.900 | 1.225–2.946 | <0.01 | 1.512 | 1.175–2.614 | 0.01 |
Pathologic N (N1/N2/N3) | 8/20/62/29 | 1.126 | 0.838–1.514 | 0.43 | — | — | — |
Pathologic T (T0/T1/T2/T3) | 54/42/13/10 | 1.443 | 1.143–1.821 | 0.02 | 1.243 | 0.915–1.688 | 0.16 |
Tumor location (lower/middle/upper) | 36/69/14 | 1.104 | 0.755–1.614 | 0.61 | — | — | — |
Alcohol (yes/no) | 74/45 | 1.053 | 0.656–1.689 | 0.83 | — | — | — |
Tobacco (yes/no/reformed) | 80/39 | 0.859 | 0.532–1.388 | 0.54 | — | — | — |
Death (dead/alive) | 46/73 | — | — | — | — | — | — |
Overall survival days (months, mean ± SD) | 37.06 ± 24.25 | — | — | — | — | — | — |
