Table 4 Results of GO function and KEGG pathway enrichment analyses.

From: Characterization of a five-microRNA signature as a prognostic biomarker for esophageal squamous cell carcinoma

Category

Term

Count of genes

P-value

GO biology process

Cytokine-mediated signaling pathway

8

2.70 × 10−4

Positive regulation of cell migration

8

2.00 × 10−3

Negative regulation of angiogenesis

5

2.95 × 10−3

Negative chemotaxis

4

4.16 × 10−3

Establishment of skin barrier

3

1.26 × 10−2

Melanocyte differentiation

3

1.55 × 10−2

Signal transduction

20

1.56 × 10−2

Thyroid gland development

3

2.37 × 10−2

Mesenchymal-epithelial cell signaling

2

2.85 × 10−2

Cornification

2

2.85 × 10−2

Transcription, DNA-templated

28

3.24 × 10−2

Positive regulation of inflammatory response

4

3.30 × 10−2

Wnt signaling pathway

6

3.43 × 10−2

Blood vessel remodeling

3

3.76 × 10−2

Lung alveolus development

3

4.20 × 10−2

Regulation of cell shape

5

4.59 × 10−2

Positive regulation of glucose transport

2

4.70 × 10−2

Negative regulation of cell cycle

3

4.89 × 10−2

KEGG pathway

cGMP-PKG signaling pathway

7

5.21 × 10−3

Gastric acid secretion

5

6.31 × 10−3

Vascular smooth muscle contraction

6

6.56 × 10−3

Inflammatory mediator regulation of TRP channels

5

1.73 × 10−2

Estrogen signaling pathway

5

1.79 × 10−2

Pathways in cancer

9

4.50 × 10−2

Aldosterone synthesis and secretion

4

4.90 × 10−2

  1. GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.