Table 1 Baseline demographic and clinical characteristics of 727 sepsis patients stratified using the delta SeMo & WBC tool.
Demographics characteristics | delta SeMo and WBC normal (N = 275) | delta SeMo or WBC abnormal (N = 324) | delta SeMo and WBC abnormal (N = 128) | P value |
|---|---|---|---|---|
Age, years | 68.9 (14.6) | 66.3 (15.4) | 66.5 (14.1) | 0.082 |
BMI, kg/m2 | 23.0 (4.6) | 22.5 (4.9) | 22.5 (5.6) | 0.358 |
Sex, male (%) | 161 (58.5) | 199 (61.4) | 64 (50.0) | 0.085 |
Site of suspected infection, N (%) | ||||
Pulmonary | 181 (65.8) | 204 (63.0) | 85 (66.4) | 0.691 |
Intra-abdominal | 19 (6.9) | 29 (9.0) | 6 (4.7) | 0.273 |
Urinary tract | 70 (25.5) | 69 (21.3) | 23 (18.0) | 0.206 |
Bacteremia | 19 (6.9) | 25 (7.7) | 9 (7.0) | 0.924 |
Unidentified infection | 20 (7.3) | 33 (10.2) | 10 (7.8) | 0.420 |
APACHE II score | 23.8 (8.0) | 24.1 (8.3) | 25.5 (7.9) | 0.156 |
Charlson Comorbidity Index | 2.4 (1.8) | 2.5 (1.9) | 2.8 (2.1) | 0.114 |
Coronary artery disease | 81 (29.5) | 73 (22.5) | 31 (24.2) | 0.144 |
Hypertension | 161 (58.5) | 181 (55.9) | 70 (55.1) | 0.740 |
COPD | 39 (14.2) | 48 (14.8) | 22 (17.2) | 0.728 |
Cancer | 51 (18.8) | 76 (23.6) | 36 (28.3) | 0.087 |
Chronic liver disease | 36 (13.1) | 41 (12.7) | 15 (11.7) | 0.928 |
Diabetes mellitus | 123 (44.7) | 141 (43.5) | 63 (49.2) | 0.544 |
History of stroke | 55 (20.0) | 56 (17.3) | 25 (19.5) | 0.673 |
Chronic kidney disease | 85 (30.9) | 93 (28.7) | 43 (33.6) | 0.579 |
Day 1 | ||||
SIRS | 2.0 (1.0) | 2.4 (0.9) | 2.5 (1.0) | <0.001 |
q-SOFA | 1.5 (0.6) | 1.6 (0.7) | 1.6 (0.7) | 0.235 |
SOFA scores | 8.4 (3.4) | 8.9 (3.7) | 9.2 (3.8) | 0.105 |
White blood cell count | 11,722.5 (5,882.4) | 15,416.2 (9,145.8) | 16,282.8 (8,643.1) | <0.001 |
Segmented neutrophil count | 9,636.2 (5,229.9) | 12,522.3 (8,274.9) | 12,765.4 (7,507.7) | <0.001 |
Lymphocyte count | 1,069.1 (930.0) | 1,233.9 (1,556.6) | 1,461.8 (1,532.6) | 0.023 |
Monocyte count | 512.6 (553.4) | 637.4 (603.6) | 842.8 (671.9) | <0.001 |
SeMo ratio | 29.8 (24.7) | 32.1 (39.7) | 18.6 (15.6) | <0.001 |
C-reactive protein, mg/L | 123.8 (109.3) | 150.1 (115.6) | 155.9 (119.8) | 0.014 |
Lactate, mmol/L | 24.2 (20.9) | 33.7 (31.9) | 33.1 (28.4) | 0.001 |
Procalcitonin | 19.9 (46.5) | 24.4 (48.4) | 29.3 (48.0) | 0.429 |
I/O, fluid balance | 308.9 (1165.3) | 534.8 (1301.9) | 710.9 (1307.9) | 0.007 |
