Table 1 Clinical characteristics of HPV/HIV-1 coinfected patients.

From: ADAR1 function affects HPV replication and is associated to recurrent human papillomavirus-induced dysplasia in HIV coinfected individuals

 

All

Recurrent dysplasia

Non- Recurrent dysplasia

p

Individuals, n (%, CI)

173 (100)

52 (30%, 95% CI: 24–37%)

121 (70%, 95% CI: 63–76%)

—

Gender, female/male (% of total)

32 (18.5)/141 (81.5)

10 (19)/42 (81)

22 (18)/99 (82)

NS

Age, years median (range)

45 (23–77)

46 (24–77)

43 (23–52)

NS

Follow-up time since first cytology, median (years)

5.8

5.6

6.1

NS

Time to first dysplasia, median years (range)

2.6 (0.7–10)

1.6 (0.7–10)

2.2 (0.1–6.9)

NS

Time since first visit to HIV clinic (years)

12.8

10.7

13.3

NS

HPV genotypes, n

    

   Low oncogenic type

 

0

13

—

   High oncogenic type

 

52

108

—

CD4 Nadir, median (range)

240 (22–993)

225 (2–576)

248 (80–993)

NS

  1. CI: confidence interval, NS: not significant after Student’s T test. Time to first dysplasia calculated from the time to first cytology. Samples were considered high oncogenic type with one or more high risk oncogenic HPV types detected.
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