Figure 2 | Scientific Reports

Figure 2

From: Collagen fibrils and proteoglycans of peripheral and central stroma of the keratoconus cornea - Ultrastructure and 3D transmission electron tomography

Figure 2

Electron micrographs of the posterior stroma at the periphery of normal and keratoconus corneas; (A) Undulating lamellae at the pre-Descemet’s membrane of the KC cornea; (B) Electron dens material (red star) in between the degenerated collagen fibrils (CFs) of the undulating lamellae shown in (A) (Osmium tetroxide fixation); (C) Degenerated CFs at the pre-Descemet’s membrane of the KC cornea (Osmium tetroxide fixation); (D,E) Large proteoglycans (PGs) around the CF in the posterior stromal lamellae of KC cornea (Cuprolinic + glutaraldehyde fixation); (F) Organised CF connected by PGs in the posterior stroma of the normal cornea. CF = Collagen fibrils, PG = Proteoglycan, L = Undulating lamellae.

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