Table 3 Pre-procedural Imaging Characteristics between Responders and Non-responders.

From: Predictive imaging for tumor response to drug-eluting microsphere transarterial chemoembolization in patients with BCLC-C advanced hepatocellular carcinoma

 

Responder (n = 50)

Non-responder (n = 36)

P value

Sorafenib usage

13 (32.5%)

5 (20.8%)

0.312

Pre-procedural Imaging Characteristics

  APHE

  

0.982

   Absent

14 (28.0%)

10 (27.8%)

 

   Present

36 (72.0%)

26 (72.2%)

 

  Washout on portal venous phase

  

0.400

   Absent

10 (20.0%)

10 (27.8%)

 

   Present

40 (80.0%)

26 (72.2%)

 

  Capsule

  

0.421

   Absent

35 (70.0%)

28 (77.8%)

 

   Present

15 (30.0%)

8 (22.2%)

 

  Tumor morphology

  

0.063

   Well-defined

41 (82.0%)

23 (63.9%)

 

   Infiltrative

9 (18.0%)

13 (36.1%)

 

  Cystic degeneration

  

0.657

   Absent

31 (62.0%)

24 (66.7%)

 

   Present

19 (38.0%)

12 (33.3%)

 

  Macroscopic vessel involvement

  

0.595

   Absent

14 (28.0%)

12 (33.3%)

 

   Present

36 (72.0%)

24 (66.7%)

 

  Exophytic growth

  

0.803

   Absent

40 (80.0%)

28 (77.8%)

 

   Present

10 (20.0%)

8 (22.2%)

 

  Intra-hepatic vascular shunt

  

0.004*

   Absent

35 (70.0%)

14 (38.9%)

 

   Present

15 (30.0%)

22 (61.1%)

 

Angiographic Characteristics

 

  Feeding artery diameter

  

0.865

   ≤microcatheter

9 (18.0%)

7 (19.4%)

 

   >microcatheter

41 (82.0%)

29 (80.6%)

 

  Number of supplying artery*

  

0.934

   Single

42 (84.0%)

30 (83.3%)

 

   Multiple

8 (16.0%)

6 (16.7%)

 

  Vascular lake phenomenon (VLP)

  

0.037*

   Absent

35 (70.0%)

32 (88.9%)

 

   Present

15 (30.0%)

4 (11.1%)

 

  HTE on CBCT

  

<0.001*

   Yes

40 (80.0%)

6 (16.7%)

 

   No

10 (20.0%)

30 (83.3%)

 

  Residual tumor blush

  

<0.001*

   No

28 (56.0%)

3 (8.3%)

 

   Yes

22 (44.0%)

33 (91.7%)

 

  Sub-stasis endpoint

  

0.720

   No

4 (8.0%)

5 (13.9%)

 

   Yes

46 (92.0%)

31 (86.1%)

 
  1. Data are expressed as number of target lesions(percentage). P values derived from the chi-square test are significant (P < 0.05*) HTE: homogeneous tumor enhancement; CBCT: cone-beam CT; DEM-TACE: Drug-eluting transarterial chemoembolization.