Figure 5 | Scientific Reports

Figure 5

From: Force spectroscopy-based simultaneous topographical and mechanical characterization to study polymer-to-polymer interactions in coated alginate microspheres

Figure 5

Colocalization of topography and stiffness maps of the microspheres. Sample topography (gold), stiffness (blue) and topography (red)- stiffness (green) overlays are shown for microsphere types (a) AP, (b) APG, (c) APP, (d) GDP. Line profiles of topography (gold) and stiffness (blue) are shown on the right of each of the maps. (e) Colocalization graphs for topography and stiffness are shown as a function of the Pearson correlation coefficient graphed as a function of x translation. One-sample t-tests were used to determine if the central points were significantly different from 0. (f) Colocalization degrees calculated from (e) are depicted for each of the microsphere types. n = at least 6 samples per group. All graphs depict mean ± standard error of the mean. Data was proved normal and then subjected to ANOVA and Tamhane post-hoc test. **p < 0.01; ***p < 0.001 in comparisons against the AP group; ###p < 0.001 for APP-GDP comparisons.

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