Figure 3 | Scientific Reports

Figure 3

From: MicroRNA-96-5p represses breast cancer proliferation and invasion through Wnt/β-catenin signaling via targeting CTNND1

Figure 3

CTNND1 is a miR-96-5p target. (A) Binding sites in the 3′-UTR of CTNND1 mRNA. Mutated sites are underlined. (B) Upregulation of CTNND1 expression in BCa via qRT-PCR. *P < 0.05. (C,D) miR-96-5p upregulation decreases CTNND1 in BCa cells. N = 3, *P < 0.05. (E) Loss of miR-96-5p in BCa cells negatively regulates wt 3′-UTR of CTNND1 but not mt 3′-UTR. N = 3; p-values as described in Fig. 1.

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