Figure 5
From: IL-33/ST2 axis promotes glioblastoma cell invasion by accumulating tenascin-C
TNC depletion decreases IL-33-driven glioma invasiveness. (A) An shRNA construct was used to knockdown TNC in U251 cells, with confirmation by WB. (B) U251 cells were transfected with sh-ctrl or sh-TNC, and invasion was assayed with a Matrigel-coated transwell migration assay. (C) U251 cells were transfected with sh-ctrl or shTNC, and migration was assayed with a transwell migration assay. Data are shown as the mean ± SEM; n = 3, NS = not significant, **p < 0.01, ***p < 0.001.
