Figure 6
From: IL-33/ST2 axis promotes glioblastoma cell invasion by accumulating tenascin-C
Schematic diagram of the regulation of glioma invasion by IL-33. Overexpression of IL-33 promotes glioma invasiveness associated with increased TNC expression. IL-33 signals through its receptor ST2 in an autocrine or paracrine manner to evoke glioma cell invasion through activation of downstream signalling cascades, including NF-κB and PI3K pathways.
