Table 1 Disease activity index (DAI) for assessment.

From: Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation

DSS dosing day

Weight loss

Stool consistency

Rectal bleeding

Score

Day 1

1–3%

1

well-formed pellets

0

normal

0

1

Day 3

4–10%

2

pasty

1

hemorrhage

2

5

Day 5

10–20%

3

liquid stools

2

gross bleeding

4

9

  1. Development of DSS-induced inflammation was daily assessed on the basis of the changes in the following parameters over time: weight of the animal, stool consistency, and presence of rectal bleeding. Final score is the sum of the assessed parameters.
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