Figure 4
Comparison of DE genes. Venn Diagram of the distribution of significant genes (adjusted p-value < 0.01) among the three comparisons, from (a) Microarray data and (b) RNA-Seq data; (a,b) Each complete circle represents the number of differentially expressed genes of a certain comparison as resulted by DEA. (c–h) Scatter plots of the log-fold change of significant genes (adjusted p-value < 0.01) shared by two or more comparisons from microarray data (as shown in a). (c) Scatter plot of the logFC of the 1,168 DE genes shared by Regenerative vs. Control and Regenerative vs. Wound healing comparisons. (d) Scatter plot of the logFC of the 575 DE genes shared by Regenerative vs. Wound healing and Wound healing vs. Control comparisons. (e) Scatter plot of the logFC of the 457 DE genes shared by Regenerative vs. Control and Wound healing vs. Control comparisons. (i–n) Scatter plots of the log-fold change of significant genes (adjusted.p-value < 0.01) shared by two or more comparisons from RNA-Seq data (as shown in b). (i) Scatter plot of the logFC of the 1,582 DE genes shared by Regenerative vs. Control and Regenerative vs. Wound healing comparisons. (j) Scatter plot of the logFC of the 177 DE genes shared by Regenerative vs. Wound healing and Wound-healing vs. Control comparisons. (k) Scatter plot of the logFC of the 145 DE genes shared by Regenerative vs. Control and Wound healing vs. Control comparisons. (f–h,l–n) Pair-wise scatter plots of the logFC of the 1,018 and 39 DE genes shared by all three comparisons from microarray and RNA-Seq data, respectively; (f,l) Regenerative vs. Control and Regenerative vs. Wound healing, (g,m) Regenerative vs. Control and Wound healing vs. Control, (H,N) Regenerative vs. Wound healing and Wound healing vs. Control.
