Figure 5
Identification of the common DE genes. (a) Venn Diagram of the initial number of genes used before differential expression analysis. This number for each platform is obtained just after the filtering and/or merging. (b–d) Venn diagrams of the distribution of DE genes (adjusted p-value < 0.01) between Microarray and RNA-seq data as well as (e–g) scatter plots of the log-fold change of the common DE genes between the two technologies for (b,e) wound healing vs. control, (c,f) regenerative vs. control, and (d,g) regenerative vs. wound healing. (h–j) Scatter plots of the log-fold change of the top DE genes (adjusted p-value < 0.01, logFC magnitudes >1) commonly identified by Microarray and RNA-seq technologies’ analyses for (h) wound healing vs. control (91 top DE genes), (i) regenerative vs. control (351 top DE genes), and (j) regenerative vs. wound healing (280 top DE genes). (k) Venn Diagram of the distribution of the top DE genes (adjusted p-value < 0.01, logFC magnitudes >1) commonly identified by the analyses of both technologies among the three comparisons.
