Figure 3

Different tolerance of ASCs and fibroblasts toward A2-P-induced cytotoxicity. Viability of ASCs or fibroblasts was measured at different cell seeding densities and exposed to various concentrations of A2-P for 4 and 7 days. The activity index was defined as a ratio of fluorescent value of alamar blue relative to that of day 1. At the same seeding density, fibroblasts exhibited relatively higher activity indexes than ASCs across all concentrations of A2-P, except at the day 7 of the 10000 cells/cm2 group. Data are presented as mean ± SD of 3 independent experiments. *p < 0.05, **P < 0.01, ***P < 0.001 relative to the ASC group of respective A2-P concentrations.