Table 3 Univariate and multivariate analysis of effects of MIF SNP rs755622 and characteristics of subjects on the risk of acute coronary syndrome.

From: MIF gene rs755622 polymorphism positively associated with acute coronary syndrome in Chinese Han population: case–control study

Characteristics

N

COR (95% CI)

P

AOR (95% CI)

P

rs755622

GG

1123

Ref.

   

CG + CC

729

1.306 (1.078–1.581)

0.006

1.278 (1.042–1.567)

0.019

Age

1852

1.009 (0.995–1.013)

0.409

  

Gender

Female

786

Ref.

   

Male

1066

1.312 (1.083–1.589)

0.005

1.086 (0.842–1.402)

0.524

Smoking

No

579

Ref.

   

Yes

1273

1.548 (1.267–1.892)

<0.001

1.498 (1.153–1.946)

0.002

BMI ≥ 24 kg/m2

No

525

Ref.

   

Yes

1326

1.419 (1.146–1.758)

0.001

1.257 (0.997–1.584)

0.053

Hypertension

No

785

Ref.

   

Yes

1067

1.671 (1.382–2.021)

<0.001

1.294 (1.054–1.591)

0.014

Diabetes

No

420

Ref.

   

Yes

1432

2.189 (1.755–2.729)

<0.001

3.692 (2.754–4.949)

<0.001

Glucose ≥ 6.1 mmol/L

No

1507

Ref.

   

Yes

354

1.903 (1.503–2.410)

<0.001

1.045 (0.790–1.381)

0.760

TG ≥ 1.71 mmol/L

No

1202

Ref.

   

Yes

650

1.069 (0.879–1.302)

0.503

  

TC ≥ 5.2 mmol/L

No

290

Ref.

   

Yes

1562

2.113 (1.641–2.721)

<0.001

1.975 (1.504–2.594)

<0.001

HDL-C < 1.04 mmol/L

No

923

Ref.

   

Yes

929

0.722 (0.598–0.872)

0.001

0.832 (0.679–1.020)

0.077

LDL-C ≥ 3.1 mmol/L

No

1761

Ref.

   

Yes

89

3.462 (2.207–5.430)

<0.001

1.965 (1.443–2.675)

<0.001

  1. BMI, body mass index; TG, total triglyceride; TC, total cholesterol; HDL–C, high–density lipoprotein–cholesterol; LDL–C, low density lipoprotein–cholesterol; COR, crude odds ratio; AOR, adjusted odds ratio.
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