Table 4 Baseline characteristics of COPD patients stratified according to response to pulmonary rehabilitation.
All COPD patients (n = 196) | Non-responder (n = 67) | ≥100 s change on CWRT or ≥30 m change on 6MWT (n = 90) | ≥100 s change on CWRT + ≥30 m change on 6MWT (n = 39) | |
|---|---|---|---|---|
Clinical characteristics | ||||
Sex, male, % | 57.7 | 52.2 | 54.4 | 64.4 |
Age, years | 63.7 (8.3) | 64.8 (8.0) | 63.3 (8.8) | 63.0 (7.7) |
Body mass index, kg/m2 | 26.2 (5.7) | 24.7 (4.6) | 26.4 (5.3) | 28.3 (7.6)* |
Fat free mass index, kg/m2 | 16.4 (2.5) | 16.0 (2.2) | 16.4 (2.6) | 17.5 (2.7)* |
FEV1, L | 1.30 (0.63) | 1.18 (0.56) | 1.32 (0.67) | 1.45 (0.63)* |
FEV1, % pred | 48.1 (19.5) | 46.4 (20.2) | 48.7 (19.9) | 49.6 (17.4) |
FEV1/FVC | 36.1 (13.0) | 33.1 (11.1) | 36.7 (13.6) | 39.7 (13.7)* |
Exercise capacity | ||||
Peak VO2, mL/min | 1106 (343) | 1080 (296) | 1097 (365) | 1177 (370) |
Peak VO2, %predicted | 60.7 (17.5) | 64.0 (17.0) | 59.6 (18.3) | 57.5 (16.0) |
6-minute walk distance, m | 419 (97) | 427 (91) | 423 (100) | 394 (97) |
6-minute walk distance, %predicted | 65.4 (15.1) | 67.1 (15.0) | 66.2 (15.2) | 60.8 (14.2) |
Change in 6-minute walk distance, m | 14 (50) | −21 (44) | 16 (39)* | 69 (30)*† |
Constant work rate test, s | 312 (230) | 333 (309) | 301 (185) | 301 (153) |
Change in constant work rate test, s | 224 (358) | −53 (205) | 321 (340)* | 473 (301)*† |
Retinal findings | ||||
CRAE, µm | 152.9 (12.3) | 152.1 (13.1) | 153.4 (12.0) | 152.8 (11.5) |
Change in CRAE, µm | 0.02 (7.2) | 1.84 (6.0) | −1.21 (6.3) | −0.37 (10.2) |
CRVE, µm | 234.8 (19.9) | 234.1 (23.6) | 235.9 (18.9) | 233.6 (15.3) |
Change in CRVE, µm | 0.61 (11.1) | 0.89 (12.4) | −0.40 (10.0) | 2.41 (10.9) |
Retinal abnormalities, % | 59 | 66 | 56 | 59 |
