Figure 4

Comparison of protease-antiprotease balance and expression of apoptotic factors between both groups. Western blot analysis of (a,b) NE (n = 11 in each group), (a,c) MMP-9 (n = 11 in each group), (a,d) MMP-12 (n = 11 in each group), (a,e)AAT (n = 11 in each group), (a,f) SLPI (n = 11 in each group), (a,g) TIMP-1 (n = 11 in each group), (a,h) Caspase-3 (n = 11 in each group), (a,i) Caspase-8 (n = 11 in each group), (a,j) Bax (n = 11 in each group), (a,k) Bcl-2 (n = 11 in each group) and (a,l) Survivin (n = 11 in each group) expression in lung tissues of emphysematous smokers and emphysematous patients with COPD. There was no significant difference between both. Data represent the mean ± SEM from three independent experiments. Full-length blots are presented in Supplementary Fig. S1.