Table 3 Absolute values of lung function indexes in healthy term controls, premature infants without bronchopulmonary dysplasia (BPD), and premature infants with BPD at different corrected ages.
From: Evolution and Determinants of Lung Function until Late Infancy among Infants Born Preterm
Control | Premature without BPD | Premature with BPD | ||
|---|---|---|---|---|
Vt (ml) | 6 mo | 64.74 ± 8.35 (n = 86) | 60.47 ± 11.62* (n = 39) | 58.41 ± 9.33*** (n = 53) |
12 mo | 88.23 ± 13.67 (n = 44) | 88.46 ± 11.5 (n = 37) | 74.09 ± 11.17*** (n = 38) | |
18 mo | 107.4 ± 14.6 (n = 20) | 102.7 ± 13.9 (n = 30) | 95.0 ± 14.8 (n = 28) | |
24 mo | 114.5 ± 8.3 (n = 10) | 117 ± 14 (n = 16) | 97.9 ± 22 (=21) | |
Rrs (kPa*s/L) | 6 mo | 4.31 ± 1.31 (n = 86) | 4.65 ± 1.48 (n = 37) | 5.43 ± 1.54*** (n = 45) |
12 mo | 3.24 ± 0.93 (n = 42) | 3.24 ± 0.82 (n = 30) | 4.06 ± 1.73** (n = 35) | |
18 mo | 2.53 ± 0.45 (n = 19) | 3.22 ± 1.05* (n = 24) | 4.34 ± 2.56** (n = 26) | |
24 mo | 2.1 ± 0.9 (n = 10) | 2.217 ± 0.39 (n = 14) | 3.182 ± 1.29* (n = 20) | |
Crs (ml/kPa) | 6 mo | 102.7 ± 29.9 (n = 86) | 84.5 ± 18.4*** (n = 37) | 75.2 ± 23.3*** (n = 45) |
12 mo | 140.9 ± 34.6 (n = 42) | 122.4 ± 42.2* (n = 30) | 101.1 ± 19.62*** (n = 35) | |
18 mo | 155.2 ± 25.4 (n = 19) | 150.3 ± 25.5 (n = 24) | 136.7 ± 30.2* (n = 26) | |
24 mo | 180 ± 33 (n = 10) | 188 ± 41 (n = 14) | 129.4 ± 50** (n = 20) | |
V’maxFRC (ml/s) | 6 mo | 202.9 ± 98.3 (n = 97) | 112.8 ± 54.2*** (n = 32) | 101.7 ± 52.1*** (n = 46) |
12 mo | 282.5 ± 117.2 (n = 68) | 227.4 ± 88.8* (n = 33) | 150.4 ± 65.6*** (n = 37) | |
18 mo | 354.7 ± 134.1 (n = 33) | 291.7 ± 110.8* (n = 29) | 203.5 ± 102.9*** (n = 26) | |
24 mo | 360.1 ± 135.2 (n = 27) | 399.6 ± 136.7 (n = 14) | 220.2 ± 138.1** (n = 20) | |
FEV0.5 (ml) | 6 mo | 235 ± 19 (n = 33) | 209.5 ± 29** (n = 10) | 198.7 ± 31.2*** (n = 25) |
12 mo | 295.8 ± 17.2 (n = 25) | 302.0 ± 25.1 (n = 8) | 242.2 ± 50.1*** (n = 20) | |
18 mo | 327.6 ± 19.9 (n = 25) | 322.7 ± 33.0 (n = 12) | 294.3 ± 57.7** (n = 22) | |
24 mo | 368 ± 26.5 (n = 14) | 363.3 ± 46.1 (n = 10) | 282.7 ± 56.4*** (n = 16) | |
FVC (ml) | 6 mo | 308.8 ± 39.2 (n = 33) | 285.2 ± 49.2 (n = 10) | 273.8 ± 55.7** (n = 25) |
12 mo | 436.4 ± 36.0 (n = 25) | 469 ± 42 (n = 8) | 355 ± 63.8*** (n = 20) | |
18 mo | 503.1 ± 41.8 (n = 25) | 501.7 ± 56.3 (n = 12) | 454.5 ± 88.0* (n = 22) | |
24 mo | 587.9 ± 55.7 (n = 14) | 582.8 ± 99.4 (n = 10) | 440.2 ± 107.7*** (n = 16) | |
FEF25–75 (ml/s) | 6 mo | 427.6 ± 29.4 (n = 33) | 364.2 ± 53.2*** (n = 10) | 355 ± 60.5*** (n = 25) |
12 mo | 523.4 ± 27.1 (n = 25) | 515.5 ± 51.5 (n = 8) | 387.7 ± 66.6*** (n = 20) | |
18 mo | 573.4 ± 31.3 (n = 25) | 554.1 ± 59.5 (n = 12) | 503.8 ± 103.8** (n = 22) | |
24 mo | 637.1 ± 41.8 (n = 14) | 626.4 ± 77.1 (n = 10) | 478.3 ± 108.6*** (n = 16) |
