Figure 1 | Scientific Reports

Figure 1

From: Real-time in vivo imaging of regional lung function in a mouse model of cystic fibrosis on a laboratory X-ray source

Figure 1

(a) Experimental image acquisition setup. Propagation-based phase contrast X-ray images of mouse lungs were acquired on a laboratory imaging setup consisting of a high brightness X-ray source with a liquid-metal-jet anode. Mice were non-surgically intubated and mechanically ventilated, then placed in a custom-built sample holder on a rotating stage for imaging. (b) Raw 2D projections were acquired over 360°, with images binned according to their time-point within the breath cycle. (c) CT volumes at each of the 15 time-points throughout the breath were then reconstructed from the binned projections, to produce a complete 4D CT dataset.

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